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    The Best Time to Take Blood Pressure Medication, According to Cardiologists

    The typical advice for when to take your antihypertensives (high blood pressure medication) has been to take it in the morning.

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  • However, there’s growing evidence that most blood pressure medications are more effective when people take them at night.

    This is largely due to a concept called chronotherapy. It is an approach to the timing of medical treatment based on circadian rhythms, the body’s natural cycle of physical changes that take place every 24 hours.

    The approach has been used to find the best times of day to treat other medical conditions, including sleep apnea, chronic kidney disease, and diabetes.

    Advantages of Medicating at Night

    Quite a few studies suggest that blood pressure medications may work best when taken at night.

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    The biggest and most significant of these was the Hygia Chronotherapy Trial. It was a six-year study of more than 19,000 people with high blood pressure.

    The researchers divided the participants into two groups.

    One group took their blood pressure medication

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